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Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.
Simon S. Rothwell, Robert G RG. Cooper, Ingrid E IE. Lundberg, Frederick W FW. Miller, Peter K PK. G
Source: Annals of the rheumatic diseases


Efficient therapy of ischaemic lesions with VEGF121-fibrin in an animal model of systemic sclerosis.
Shadab S. Allipour Birgani, Marion M. Mailänder, Ines I. Wasle, Hermann H. Dietrich, Johann J. Grube
Source: Annals of the rheumatic diseases


Decreased expression of neuropilin-1 as a novel key factor contributing to peripheral microvasculopathy and defective angiogenesis in systemic sclerosis.
Eloisa E. Romano, Inês I. Chora, Mirko M. Manetti, Celestina C. Mazzotta, Irene I. Rosa, Silvia S. B
Source: Annals of the rheumatic diseases


Impact of baseline anti-cyclic citrullinated peptide-2 antibody concentration on efficacy outcomes following treatment with subcutaneous abatacept or adalimumab: 2-year results from the AMPLE trial.
Jeremy J. Sokolove, Michael M. Schiff, Roy R. Fleischmann, Michael E ME. Weinblatt, Sean E SE. Conno
Source: Annals of the rheumatic diseases


Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors.
W W. Gao, T T. McGarry, C C. Orr, J J. McCormick, D J DJ. Veale, U U. Fearon
Source: Annals of the rheumatic diseases


Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose.
Catherine L CL. Hill, Lynette M LM. March, Dawn D. Aitken, Susan E SE. Lester, Ruth R. Battersby, Kr
Source: Annals of the rheumatic diseases


Antibodies against carbamylated proteins are present in primary Sjögren's syndrome and are associated with disease severity.
Brith B. Bergum, Catalin C. Koro, Nicolas N. Delaleu, Magne M. Solheim, Annelie A. Hellvard, Veronik
Source: Annals of the rheumatic diseases


MicroRNA markers of inflammation and remodelling in temporal arteries from patients with giant cell arteritis.
Stefania S. Croci, Alessandro A. Zerbini, Luigi L. Boiardi, Francesco F. Muratore, Alessandra A. Bis
Source: Annals of the rheumatic diseases


Efficacy and safety of subcutaneous tabalumab in patients with systemic lupus erythematosus: results from ILLUMINATE-1, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study.
D A DA. Isenberg, M M. Petri, K K. Kalunian, Y Y. Tanaka, M B MB. Urowitz, R W RW. Hoffman, M M. Mor
Source: Annals of the rheumatic diseases


Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway.
Elena E. López-Isac, Diana D. Campillo-Davo, Lara L. Bossini-Castillo, Sandra G SG. Guerra, Shervin
Source: Annals of the rheumatic diseases




Featured Programs
The 2017 CUA Guideline on Adult OAB
Obesity Management
Cow’s Milk Protein Allergy
Heart Failure Management
Chronic Venous Disease
Allergic Rhinitis
An Ounce of Prevention: Early Intervention against Obesity-Related Comorbidity
Halting Obesity Progression
Hypothyroidism and Primary Care
Acute Muscle & Joint Pain Management
Managing The Burden Of Psoriasis
Practical Management of the Bipolar Spectrum
Screening of Cervical Cancer in Women ≥30
Fertility in Primary Care
Living and Aging Well with Overactive Bladder
Pain: Reducing Gender Bias in Diagnosis
Eczema Management in Primary Care
Educating Patients with Heart Disease about Dairy
Biosimilars Innovation
Paediatric Influenza: An Algorithm
Diabetes Treatments for Patients with CKD
Pharmacogenomics in Primary Care
Simplifying Management with GLP-1RAs
Seasonal Influenza Immunization in Canada
Newer insulin analogues for T2D
Protecting Infants and Toddlers from Seasonal Influenza
Face To Face With Acne
Diabetes Management in the Digital Age
Nicotine Replacement Therapy
Suicide: Facing the Difficult Topic Together
Assessing Airway Disease
T2D & Dyslipidemia: New Generation of Management
Emergency Contraception (EC)
Functional Constipation
Hepatitis C: Role of the Primary Care Physician
NACI Immunization Updates
Patient-Centric Prostate Cancer
Vasomotor Symptoms in Menopause
An Update on Stroke Prevention and Atrial Fibrillation
Nutritional Interventions to Lower CVD Risk
Idiopathic Pulmonary Fibrosis
Adults with Binge Eating Disorder (BED)
Publications in Practice 2017
Pharmacotherapy in Type 2 Diabetes
Ouch! My back is killing me!
Preventing Meningococcal Disease
Childhood Measles, Mumps and Rubella (MMR) Vaccination in Canada
Adult Pneumococcal Vaccination
Chronic Hand Dermatitis